Yes. A friend of mine on the forum sent me this link that discussed exactly what you mention:
I think I would go with regular PHD and use an off axis guider to take advantage of the full scope aperture. Probably could guide on the core of a comet.
Wes, Southport NC
PMC-8, ES ED 127, 10" LX200GPS, Astro-Tech 8" Newt, ETX-90
Polemaster, Orion ST-80 and SAG
Electrical Engineer, Retired