I was reading that your scope goes in the wrong direction and I have to ask the obvious question: Do you have your longitude set correctly? I am at about the same longitude as you here in Kentucky and I have mine set to 84 degrees WEST longitude. Is it possible that you have yours set to EAST? Just want to rule out the easy things first.
Location: Nicholasville, KY
Mount: Explore Scientific Exos-2
Scope: Explore Scientific ED102CF, Orion 60mm guidescope
Camera: QHY163C and QHY5L-ii
Filter: Optolong L-eNhance 2"
Software: ASCOM, PHD2, CDC, Stellarium, Sharpcap Pro, NINA, Deep Sky Stacker, Affinity Photo, Lightroom
Computer: ASRock X570 Steel Legend, AMD Ryzen 7 3700X 8-Core Processor, 3600Mhz
Extras: Lots of 3D printed parts I designed for improved usability